Anti-Human CD22 Recombinant Antibody (TAB-183-F(E))
CAT#: TAB-183-F(E)
Recombinant monoclonal antibody to CD22. It is an anti-CD22 mouse monoclonal antibody designed for the treatment of cancer.
Tested Data
Gene Expression
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SDS-PAGE
Figure 1 Anti-Human CD22 Recombinant Antibody (TAB-183-F(E)) in SDS-PAGE
SDS-PAGE analysis of TAB-183-F(E) in non-reduced (Lane 1). Gel stained for 30 minutes with Coomassie Blue. And non-reduced protein migrates as 70 kDa.
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SEC-HPLC
Figure 2 Anti-Human CD22 Recombinant Antibody (TAB-183-F(E)) in HPLC
HPLC analysis of TAB-183-F(E) shows the purity is>95%.
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Normal Tissue
Figure 1 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_A_7_8.jpg
Normal Tissue
Figure 2 Spleen
Cells in red pulp
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_B_7_4.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (Daudi, REH, U-698, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Fv - disulfide stabilized
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- FuncS, IF, Neut, ELISA, FC, IP, ICC
- MW
- 63.5 kDa
- Related Disease
- Hairy cell leukemia (HCL)
Product Property
- Purity
- Purity >95% by SDS-PAGE.
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Applications
- Application Notes
- The CD22 antibody has been reported in applications of PK, Cyt.
Target
- Alternative Names
- Moxetumomab pasudotox;1020748-57-5;CAT-8015;HA22;R490A;BL22 immunotoxin;CD22;CD22 molecule;CD22 antigen;B-cell receptor CD22;sialic acid binding Ig like lectin 2;SIGLEC 2;SIGLEC2;BL-CAM;T-cell surface antigen Leu-14;B-lymphocyte cell adhesion molecule;sia
- Gene ID
- 933
- UniProt ID
- P20273
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(Creative Biolabs Cat# TAB-183-F(E), RRID: AB_3111855)
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Biosimilar Overview
Please refer to Moxetumomab Pasudotox Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Moxetumomab Pasudotox.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-198 | Humanized Anti-CD22 Recombinant Antibody (clone Inotuzumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | Humanized (from mouse) IgG4, κ |
| TAB-1725CL | Human Anti-CD22 Recombinant Antibody (TAB-1725CL) | Block, Cyt, ELISA, FuncS | Humanized IgG |
| TAB-1729CL | Human Anti-CD22 Recombinant Antibody (TAB-1729CL) | IF, FC | Humanized IgG |
| TAB-1725CL-S(P) | Human Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1725CL-S(P)) | Block, Cyt, ELISA, FuncS | Humanized scFv |
| TAB-1729CL-S(P) | Human Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1729CL-S(P)) | IF, FC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-047-F(E) | Anti-Human CD22 Recombinant Antibody Fab Fragment(Bectumomab) | ELISA, FC, IP, FuncS, IF, Neut, WB | Fab' - G2a - kappa |
| TAB-1714CL | Mouse Anti-CD22 Recombinant Antibody (TAB-1714CL) | ELISA, WB | Mouse IgG |
| TAB-1714CL-S(P) | Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1714CL-S(P)) | ELISA, WB | Mouse scFv |
| TAB-1723CL-S(P) | Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1723CL-S(P)) | Inhib | Mouse scFv |
| TAB-1728CL-S(P) | Anti-Human CD22 Recombinant Antibody scFv Fragment (RFB4) | IF, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L048E | anti-CD22 immunotoxin RFB4 (scFv)-PE | Cytotoxicity assay, Functional assay | |
| AGTO-L048D | anti-CD22 immunotoxin RFB4 (scFv)-DT | Cytotoxicity assay, Functional assay | |
| AGTO-L048G | anti-CD22 immunotoxin RFB4 (scFv)-Gel | Cytotoxicity assay, Functional assay | |
| AGTO-L048R | anti-CD22 immunotoxin RFB4 (scFv)-RTA | Cytotoxicity assay, Functional assay | |
| AGTO-L048S | anti-CD22 immunotoxin RFB4 (scFv)-Sap | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0196CL | Anti-Human CD22 Recombinant Antibody (hLL2) | Inhib, Cyt, FC, WB | |
| TAB-0197CL | Anti-Human CD22 Recombinant Antibody (hLL2-Cys) | ELISA, In vivo | |
| TAB-1722CL | Human Anti-CD22 Recombinant Antibody (TAB-1722CL) | ELISA, FC, FuncS | Human antibody |
| TAB-0196CL-F(E) | Anti-Human CD22 Recombinant Antibody Fab Fragment (hLL2) | ELISA, In vivo | |
| TAB-0197CL-F(E) | Anti-Human CD22 Recombinant Antibody Fab Fragment (hLL2-Cys) | ELISA, In vivo |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1724CL | Human Anti-CD22 Recombinant Antibody (TAB-1724CL) | Inhib | Chimeric (mouse/human) IgG1, κ |
| TAB-1724CL-S(P) | Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1724CL-S(P)) | Inhib | Mouse scFv |
| TAB-1724CL-F(E) | Human Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-1724CL-F(E)) | Inhib | Chimeric (mouse/human) Fab |
| TAB-001LC | Human Anti-CD22 Recombinant Antibody (TAB-001LC) | ELISA | Chimeric antibody (mouse/human) |
| TAB-001LC-S(P) | Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-001LC-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-001LC | Recombinant Anti-Human CD22 Antibody (Fab glycosylation) | ELISA, FC | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-111LC | Recombinant Anti-Human CD22 Antibody (Fc glycosylation) | ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-315CQ | Rat Anti-CD22 Recombinant Antibody (clone 2D6) | Block | Rat IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0545 | Hi-Affi™ Rabbit Anti-CD22 Recombinant Antibody (clone DS545AB) | IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0204-LSX | Human Anti-CD22 Recombinant Antibody (clone RFB4-PE38) | Cyt, RIA, FuncS, FC, PK, Neut, ELISA | Chimeric IgG |
| HPAB-0205-LSX | Human Anti-CD22 Recombinant Antibody (clone HuLL2) | ELISA, FC | Human IgG |
| HPAB-0206-LSX | Human Anti-CD22 Recombinant Antibody (clone MJ-7) | ELISA, FC, WB | Human IgG |
| HPAB-1899LY | Mouse Anti-CD22 Recombinant Antibody (HPAB-1899LY) | ELISA, Inhib | Mouse IgG |
| HPAB-1900LY | Mouse Anti-CD22 Recombinant Antibody (HPAB-1900LY) | ELISA, Inhib | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0194-LSX-S(P) | Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0194-LSX-S(P)) | ELISA | Mouse scFv |
| HPAB-0195-LSX-S(P) | Human Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0195-LSX-S(P)) | ELISA | Human scFv |
| HPAB-0196-LSX-S(P) | Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0196-LSX-S(P)) | ELISA | Mouse scFv |
| HPAB-0197-LSX-S(P) | Human Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0197-LSX-S(P)) | ELISA | Human scFv |
| HPAB-0198-LSX-S(P) | Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0198-LSX-S(P)) | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0194-LSX-F(E) | Mouse Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0194-LSX-F(E)) | ELISA | Mouse Fab |
| HPAB-0195-LSX-F(E) | Human Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0195-LSX-F(E)) | ELISA | Human Fab |
| HPAB-0196-LSX-F(E) | Mouse Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0196-LSX-F(E)) | ELISA | Mouse Fab |
| HPAB-0197-LSX-F(E) | Human Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0197-LSX-F(E)) | ELISA | Human Fab |
| HPAB-0198-LSX-F(E) | Mouse Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0198-LSX-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-176 | Afuco™ Anti-CD22 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-176) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-198 | Afuco™ Anti-CD22 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-198) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY50 | AbPlus™ Anti-CD22 Magnetic Beads (DM13) | IP, Protein Purification | |
| VS-0724-YC918 | AbPlus™ Anti-Cd22 Magnetic Beads (VS-0724-YC918) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY24 | CytoStream™ Mouse Anti-CD22 Recombinant Antibody (VS-0225-XY24) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY357 | Anti-CD22 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1143 | Anti-Human CD22 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY82 | Human Anti-CD22 (clone Inotuzumab) scFv-Fc Chimera | ELISA | Human IgG4, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC225 | Recombinant Anti-CD22 Vesicular Antibody, EV Displayed (VS-0425-YC225) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC201 | Recombinant Anti-CD22 (Epitope A x Epitope B) Biparatopic Antibody, Tandem scFv | ELISA, FC, ICC, IF, IP, Neut | Tandem scFv |
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